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UoH Researchers Develop New Metal Alloys for Medical Implants

Researchers at the University of Hyderabad (UoH), collaborating with IIT Delhi, IIT Bhubaneswar, and CSIR-CECRI Karaikudi, have developed a new family of metal alloys potentially useful for medical implants like hip joints and bone plates.

The team focused on titanium-cobalt-chromium (TiCoCr)-based multi-principal element alloys (MPEAs) combining these metals in equal or near-equal amounts. Unlike conventional implants that may corrode or have stiffness mismatch leading to bone stress and implant loosening, these new alloys show promise in overcoming these issues.

Laboratory tests indicated that the alloys possess high strength, wear resistance, and corrosion resistance in body-like fluids. Importantly, their flexibility is closer to natural bone, potentially reducing implant loosening risk.

Cell studies showed good biocompatibility with no toxic effects and support for healthy cell growth. The research findings were published in Advanced Healthcare Materials, an international peer-reviewed journal.

The work is part of doctoral research at UoH’s School of Engineering Sciences and Technology, supervised by Prof. Koteswararao V. Rajulapati. Further testing and clinical trials are needed before medical application.

Central Universities in Telangana

Frequently Asked Questions

What metals constitute the new alloys developed by UoH researchers?

The new alloys are composed of titanium, cobalt, and chromium combined in equal or near-equal proportions.

What problems with conventional metal implants do these new alloys address?

The new alloys aim to reduce wear and corrosion, prevent metal ion release into tissues, and better match the flexibility of natural bone to reduce implant loosening.

How was the biocompatibility of these alloys tested?

Cell-based studies were conducted which indicated no toxic effects and supported healthy cell growth, demonstrating good biocompatibility.

Where were the research findings published?

The findings were published in Advanced Healthcare Materials, an international peer-reviewed journal by Wiley.

Who supervised the research at University of Hyderabad?

The research was supervised by Prof. Koteswararao V. Rajulapati at the School of Engineering Sciences and Technology, UoH.

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Alok Kumar
Written by Alok Kumar CentralUniversity.in Team · 416 articles

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